Hirudin™ was produced through high density fermentation system, multi-stage membrane enrichment process,continuous ion exchange separation and purification and freeze-drying technique,featured as below:

Safety Natural raw material, controlled process and no residual solvents.It is directly acting on thrombin without endogenous cofactors so it does not cause bleeding.

High-activity Since 1991 SungenBio has been started developing r-hirudin and constructing efficient secretion expression vector.The mutant gene of hirudin HV2 was synthesized by PCR.Its activity reaches 13800ATU/mg.

High-stability R-hirudin changed Asn to Lys,causing the rise of isoelectric point.So it has the function of heat resistance,acid-resistance,alkali-resistance and antiprotease.

High-production Comparing all kinds of gene mutants, expression vectors,signal peptides,host strains and their yields under different conditions,SungenBio has constructed high-producing strain.Each milliliter contains 6000 units hirudin.The hirudin materials,need to cultivate for 1000 years,are produced by two 10 tons tanks in one year.